Rapid Flow-Based Peptide Synthesis
A flow-based solid-phase peptide synthesis methodology that enables the incorporation of an amino acid residue every 1.8 min under automatic control or every 3 min under manual control is described. This is accomplished by passing a stream of reagent through a heat exchanger into a low volume, low b...
Main Authors: | Heider, Patrick L., Adamo, Andrea, Vinogradov, Alexander A., Li, Xiyuan, Berger, Tatiana, Policarpo, Rocco L., Zhang, Chi, Zou, Yekui, Liao, Xiaoli, Spokoyny, Alexander M., Jensen, Klavs F., Pentelute, Bradley L., Simon, Mark, Mong, Surin Khai |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Wiley Blackwell
2015
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Online Access: | http://hdl.handle.net/1721.1/96181 https://orcid.org/0000-0001-9519-7456 https://orcid.org/0000-0003-1632-5195 https://orcid.org/0000-0001-5474-4273 https://orcid.org/0000-0001-7192-580X https://orcid.org/0000-0002-5508-0963 |
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