Rapid Flow-Based Peptide Synthesis

A flow-based solid-phase peptide synthesis methodology that enables the incorporation of an amino acid residue every 1.8 min under automatic control or every 3 min under manual control is described. This is accomplished by passing a stream of reagent through a heat exchanger into a low volume, low b...

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Bibliographic Details
Main Authors: Heider, Patrick L., Adamo, Andrea, Vinogradov, Alexander A., Li, Xiyuan, Berger, Tatiana, Policarpo, Rocco L., Zhang, Chi, Zou, Yekui, Liao, Xiaoli, Spokoyny, Alexander M., Jensen, Klavs F., Pentelute, Bradley L., Simon, Mark, Mong, Surin Khai
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2015
Online Access:http://hdl.handle.net/1721.1/96181
https://orcid.org/0000-0001-9519-7456
https://orcid.org/0000-0003-1632-5195
https://orcid.org/0000-0001-5474-4273
https://orcid.org/0000-0001-7192-580X
https://orcid.org/0000-0002-5508-0963

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