Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
Reprogramming of human somatic cells uses readily accessible tissue, such as skin or blood, to generate embryonic-like induced pluripotent stem cells (iPSCs). This procedure has been applied to somatic cells from patients who are classified into a disease group, thus creating “disease-specific” iPSC...
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Format: | Article |
Language: | en_US |
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Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/96182 |