Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

Reprogramming of human somatic cells uses readily accessible tissue, such as skin or blood, to generate embryonic-like induced pluripotent stem cells (iPSCs). This procedure has been applied to somatic cells from patients who are classified into a disease group, thus creating “disease-specific” iPSC...

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Bibliographic Details
Main Authors: Saha, Krishanu, Jaenisch, Rudolf
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96182

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