Multimodality Imaging Atlas of Coronary Atherosclerosis

NEW HIGH-RESOLUTION IMAGING TECHNOLOGIES HAVE ENHANCED OUR UNDERSTANDING OF THE CORONARY atherosclerotic disease process, and this atlas provides a multimodality pictorial review of the development of histologically verified coronary atherosclerosis. A modified American Heart Association classificat...

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Main Authors: Donnelly, Patrick, Maurovich-Horvat, Pal, Vorpahl, Marc, Nakano, Masataka, Kaple, Ryan K., Warger, William, Tanaka, Atsushi, Tearney, Guillermo, Virmani, Renu, Hoffmann, Udo
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96193
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author Donnelly, Patrick
Maurovich-Horvat, Pal
Vorpahl, Marc
Nakano, Masataka
Kaple, Ryan K.
Warger, William
Tanaka, Atsushi
Tearney, Guillermo
Virmani, Renu
Hoffmann, Udo
author2 Harvard University--MIT Division of Health Sciences and Technology
author_facet Harvard University--MIT Division of Health Sciences and Technology
Donnelly, Patrick
Maurovich-Horvat, Pal
Vorpahl, Marc
Nakano, Masataka
Kaple, Ryan K.
Warger, William
Tanaka, Atsushi
Tearney, Guillermo
Virmani, Renu
Hoffmann, Udo
author_sort Donnelly, Patrick
collection MIT
description NEW HIGH-RESOLUTION IMAGING TECHNOLOGIES HAVE ENHANCED OUR UNDERSTANDING OF THE CORONARY atherosclerotic disease process, and this atlas provides a multimodality pictorial review of the development of histologically verified coronary atherosclerosis. A modified American Heart Association classification scheme system based on morphological plaque features and the propensity of plaque for thrombosis or cause of sudden cardiac death has recently been proposed. This classification scheme incorporates 5 categories of coronary atherosclerotic lesions (Table 1) (1 and 2). These categories include nonatherosclerotic lesions (intimal thickening and intimal xanthoma) and progressive atherosclerotic lesions (pathological intimal thickening, fibroatheroma, thin fibrous cap atheroma, rupture, erosion, calcified nodule, and fibrocalcific plaque). The description of these categories is based on the accretion of lipid in relationship to fibrous cap formation, lipid pool transition into necrotic core, the thinning or thickening of fibrous cap, and presence of thrombosis. Furthermore, plaque characteristics such as angiogenesis, intraplaque hemorrhage, inflammation, calcification, cell death, and proteolysis are presented as descriptive terms along with features like culprit lesion associated with thrombus. This multimodality imaging atlas of ex vivo human hearts illustrates this morphological classification through computed tomography (CT), intravascular ultrasound (IVUS), optical frequency domain imaging (OFDI) and corresponding histological characteristics.
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spelling mit-1721.1/961932022-09-30T10:35:10Z Multimodality Imaging Atlas of Coronary Atherosclerosis Donnelly, Patrick Maurovich-Horvat, Pal Vorpahl, Marc Nakano, Masataka Kaple, Ryan K. Warger, William Tanaka, Atsushi Tearney, Guillermo Virmani, Renu Hoffmann, Udo Harvard University--MIT Division of Health Sciences and Technology Virmani, Renu NEW HIGH-RESOLUTION IMAGING TECHNOLOGIES HAVE ENHANCED OUR UNDERSTANDING OF THE CORONARY atherosclerotic disease process, and this atlas provides a multimodality pictorial review of the development of histologically verified coronary atherosclerosis. A modified American Heart Association classification scheme system based on morphological plaque features and the propensity of plaque for thrombosis or cause of sudden cardiac death has recently been proposed. This classification scheme incorporates 5 categories of coronary atherosclerotic lesions (Table 1) (1 and 2). These categories include nonatherosclerotic lesions (intimal thickening and intimal xanthoma) and progressive atherosclerotic lesions (pathological intimal thickening, fibroatheroma, thin fibrous cap atheroma, rupture, erosion, calcified nodule, and fibrocalcific plaque). The description of these categories is based on the accretion of lipid in relationship to fibrous cap formation, lipid pool transition into necrotic core, the thinning or thickening of fibrous cap, and presence of thrombosis. Furthermore, plaque characteristics such as angiogenesis, intraplaque hemorrhage, inflammation, calcification, cell death, and proteolysis are presented as descriptive terms along with features like culprit lesion associated with thrombus. This multimodality imaging atlas of ex vivo human hearts illustrates this morphological classification through computed tomography (CT), intravascular ultrasound (IVUS), optical frequency domain imaging (OFDI) and corresponding histological characteristics. 2015-03-25T18:57:32Z 2015-03-25T18:57:32Z 2010-08 Article http://purl.org/eprint/type/JournalArticle 1936878X http://hdl.handle.net/1721.1/96193 Donnelly, Patrick, Pál Maurovich-Horvat, Marc Vorpahl, Masataka Nakano, Ryan K. Kaple, William Warger, Atsushi Tanaka, Guillermo Tearney, Renu Virmani, and Udo Hoffmann. “Multimodality Imaging Atlas of Coronary Atherosclerosis.” JACC: Cardiovascular Imaging 3, no. 8 (August 2010): 876–880. © 2010 American College of Cardiology Foundation en_US http://dx.doi.org/10.1016/j.jcmg.2010.06.006 JACC Cardiovascular Imaging Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Elsevier Elsevier
spellingShingle Donnelly, Patrick
Maurovich-Horvat, Pal
Vorpahl, Marc
Nakano, Masataka
Kaple, Ryan K.
Warger, William
Tanaka, Atsushi
Tearney, Guillermo
Virmani, Renu
Hoffmann, Udo
Multimodality Imaging Atlas of Coronary Atherosclerosis
title Multimodality Imaging Atlas of Coronary Atherosclerosis
title_full Multimodality Imaging Atlas of Coronary Atherosclerosis
title_fullStr Multimodality Imaging Atlas of Coronary Atherosclerosis
title_full_unstemmed Multimodality Imaging Atlas of Coronary Atherosclerosis
title_short Multimodality Imaging Atlas of Coronary Atherosclerosis
title_sort multimodality imaging atlas of coronary atherosclerosis
url http://hdl.handle.net/1721.1/96193
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