Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1998.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2005
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| Online Access: | http://hdl.handle.net/1721.1/9623 |
| _version_ | 1811072468137279488 |
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| author | Merrilees, N. Katherine (Ngaire Katherine), 1974- |
| author2 | Munther Daleh. |
| author_facet | Munther Daleh. Merrilees, N. Katherine (Ngaire Katherine), 1974- |
| author_sort | Merrilees, N. Katherine (Ngaire Katherine), 1974- |
| collection | MIT |
| description | Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1998. |
| first_indexed | 2024-09-23T09:06:26Z |
| format | Thesis |
| id | mit-1721.1/9623 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T09:06:26Z |
| publishDate | 2005 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/96232020-07-14T22:04:06Z Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease Design of control systems for ultrasound arrays for induced hyperthermia Merrilees, N. Katherine (Ngaire Katherine), 1974- Munther Daleh. Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Electrical Engineering and Computer Science Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1998. Includes bibliographical references (leaf 102). Heat transfer in tissue during induced hyperthettnia treatments for prostate disease can be modeled as a multi-input multi-output (MIMO) system. For both focused and unfocused ultrasound arrays, the control of this MIMO system can follow either of two paths. First, a method of system identification can be used to derive a system model from which a gain matrix for a controller can be calculated with methods like that of the linear quadratic regulator (LQR). Second, a trial and error controller can be designed and tuned for each new treatment. Although the first option has clear benefits, this work shows that, with MRI thermometry, the ti.me delay in the temperature feedback loop is sufficient to make any method of system identification difficult within the ti.me constraints of a clinical setting. A proportional plus integrator plus derivative (PID) controller was designed to control the system in computer simulations. This single-input, single-output (SISO) controller was weighted to better control the system by providing parameters scaled to compensate for the geometry of the treatment and thermal coupling of tissue. While the controller performed very well under the conditions for which it was tuned, the level of performance decreased when the parameters of the simulation, such as the rate of perfusion in the tissue were altered. For the unfocused array, a program was written in C++ to run the array and implement the controller for a hyperthermia treatment using MRI thermometry for the feedback signal. by N. Katherine Merrilees. M.Eng. 2005-08-19T19:00:47Z 2005-08-19T19:00:47Z 1998 1998 Thesis http://hdl.handle.net/1721.1/9623 42279103 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 109 leaves 8186363 bytes 8186122 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Electrical Engineering and Computer Science Merrilees, N. Katherine (Ngaire Katherine), 1974- Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease |
| title | Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease |
| title_full | Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease |
| title_fullStr | Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease |
| title_full_unstemmed | Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease |
| title_short | Design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease |
| title_sort | design of control systems for focused and unfocused intracavitary ultrasound arrays for the thermal treatment of prostate disease |
| topic | Electrical Engineering and Computer Science |
| url | http://hdl.handle.net/1721.1/9623 |
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