A systematic analysis of the PARP protein family identifies new functions critical for cell physiology
The poly(ADP-ribose) polymerase (PARP) family of proteins use NAD[superscript +] as their substrate to modify acceptor proteins with ADP-ribose modifications. The function of most PARPs under physiological conditions is unknown. Here, to better understand this protein family, we systematically analy...
Main Authors: | Vyas, Sejal, Chesarone-Cataldo, Melissa, Todorova, Tanya, Huang, Yun-Han, Chang, Paul |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2015
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Online Access: | http://hdl.handle.net/1721.1/96281 |
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