MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

Previous investigations of the core gene regulatory circuitry that controls the pluripotency of embryonic stem (ES) cells have largely focused on the roles of transcription, chromatin and non-coding RNA regulators. Alternative splicing represents a widely acting mode of gene regulation, yet its role...

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Bibliographic Details
Main Authors: Han, Hong, Irimia, Manuel, Ross, P. Joel, Sung, Hoon-Ki, Alipanahi, Babak, David, Laurent, Golipour, Azadeh, Gabut, Mathieu, Michael, Iacovos P., Nachman, Emil N., Trcka, Dan, Thompson, Tadeo, O’Hanlon, Dave, Slobodeniuc, Valentina, Barbosa-Morais, Nuno L., Moffat, Jason, Frey, Brendan J., Nagy, Andras, Ellis, James, Wrana, Jeffrey L., Blencowe, Benjamin J., Wang, Eric T, Burge, Christopher B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96291

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http://hdl.handle.net/1721.1/96291

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