Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate the presence of the potentially lethal mendelian long-QT syndrome (LQTS). Using...
Main Authors: | Wang, Xinchen, Kellis, Manolis, Boyer, Laurie Ann |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2015
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Online Access: | http://hdl.handle.net/1721.1/96325 https://orcid.org/0000-0003-3491-4962 |
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