A Conditional System to Specifically Link Disruption of Protein-Coding Function with Reporter Expression in Mice
Conditional gene deletion in mice has contributed immensely to our understanding of many biological and biomedical processes. Despite an increasing awareness of nonprotein-coding functional elements within protein-coding transcripts, current gene-targeting approaches typically involve simultaneous a...
Main Authors: | Chiou, Shin-Heng, Kim-Kiselak, Caroline, Risca, Viviana I., Heimann, Megan, Chuang, Chen-Hua, Burds, Aurora A., Greenleaf, William J., Jacks, Tyler E., Feldser, David M., Winslow, Monte M. |
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Other Authors: | Koch Institute for Integrative Cancer Research at MIT |
Format: | Article |
Language: | en_US |
Published: |
Elsevier B.V.
2015
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Online Access: | http://hdl.handle.net/1721.1/96530 https://orcid.org/0000-0001-5785-8911 |
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