A Conditional System to Specifically Link Disruption of Protein-Coding Function with Reporter Expression in Mice

A Conditional System to Specifically Link Disruption of Protein-Coding Function with Reporter Expression in Mice

Conditional gene deletion in mice has contributed immensely to our understanding of many biological and biomedical processes. Despite an increasing awareness of nonprotein-coding functional elements within protein-coding transcripts, current gene-targeting approaches typically involve simultaneous a...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Chiou, Shin-Heng, Kim-Kiselak, Caroline, Risca, Viviana I., Heimann, Megan, Chuang, Chen-Hua, Burds, Aurora A., Greenleaf, William J., Jacks, Tyler E., Feldser, David M., Winslow, Monte M.
Бусад зохиолчид:	Koch Institute for Integrative Cancer Research at MIT
Формат:	Өгүүллэг
Хэл сонгох:	en_US
Хэвлэсэн:	Elsevier B.V. 2015
Онлайн хандалт:	http://hdl.handle.net/1721.1/96530 https://orcid.org/0000-0001-5785-8911

Ижил төстэй зүйлс

Recombinase-based conditional and reversible gene regulation via XTR alleles
-н: Robles-Oteiza, Camila, зэрэг
Хэвлэсэн: (2016)

Response and Resistance to NF-κB Inhibitors in Mouse Models of Lung Adenocarcinoma
-н: Xue, Wen, зэрэг
Хэвлэсэн: (2011)

Investigation of the role of chromosome missegregation in embryo development and in tumorigenesis
-н: Burds, Aurora A. (Aurora Ann), 1973-
Хэвлэсэн: (2005)

Circadian Rhythm Disruption Promotes Lung Tumorigenesis
-н: Papagiannakopoulos, Thales, зэрэг
Хэвлэсэн: (2018)

Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma
-н: Chen, Guoan, зэрэг
Хэвлэсэн: (2014)

Suppression of Lung Adenocarcinoma Progression by Nkx2-1
-н: Winslow, Monte Meier, зэрэг
Хэвлэсэн: (2011)

Maternal immune activation in mice disrupts proteostasis in the fetal brain
-н: Kalish, Brian T., зэрэг
Хэвлэсэн: (2022)

Maternal immune activation in mice disrupts proteostasis in the fetal brain
-н: Kalish, Brian T, зэрэг
Хэвлэсэн: (2021)

Stage-specific sensitivity to p53 restoration during lung cancer progression
-н: Feldser, David M., зэрэг
Хэвлэсэн: (2012)

Strategies to Achieve Conditional Gene Mutation in Mice
-н: Gierut, J. J., зэрэг
Хэвлэсэн: (2018)

Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival
-н: Gocheva, Vasilena, зэрэг
Хэвлэсэн: (2018)

In Vivo Delivery of Lenti-Cre or Adeno-Cre into Mice Using Intranasal Instillation
-н: Gierut, J. J., зэрэг
Хэвлэсэн: (2018)

Hyperglycaemia disrupts conducted vasodilation in the resistance vasculature of db/db mice
-н: Lemmey, H, зэрэг
Хэвлэсэн: (2018)

Coding for satellite channels with co-channel and intersymbol interference
-н: Lee, Whay Chiou
Хэвлэсэн: (2005)

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes.
-н: Dalton, D, зэрэг
Хэвлэсэн: (1993)

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma
-н: Meylan, Etienne, зэрэг
Хэвлэсэн: (2014)

Endogenous T Cell Responses to Antigens Expressed in Lung Adenocarcinomas Delay Malignant Tumor Progression
-н: DuPage, Michel J., зэрэг
Хэвлэсэн: (2014)

Selective Killing of K-ras Mutant Cancer Cells by Novel Small Molecule Inducers of Oxidative Stress
-н: Shaw, Alice, зэрэг
Хэвлэсэн: (2011)

AU040320 defciency leads to disruption of acrosome biogenesis and infertility in homozygous mutant mice
-н: Guidi, LG, зэрэг
Хэвлэсэн: (2018)

Autistic behavior is a common outcome of biallelic disruption of PDZD8 in humans and mice
-н: Pantiru, AD, зэрэг
Хэвлэсэн: (2025)

Complete deletion of Apc results in severe polyposis in mice
-н: Bronson, Roderick T., зэрэг
Хэвлэсэн: (2014)

Enabling Disruptive Innovations in High Growth Organizations when Architecting an Enterprise
-н: Niday, Tyler C.
Хэвлэсэн: (2022)

Electrophysiological and mechanical properties of ventricular myocytes isolated from wild-type mice and mice with disruption of the neuronal nitric oxide synthase gene
-н: Sears, C, зэрэг
Хэвлэсэн: (2001)

Antipruritic properties of topical Channa striatus extract on stratum corneum disruption-itch mice model
-н: Fauzi, Irfan, зэрэг
Хэвлэсэн: (2022)

Autosomal dominant growth hormone deficiency disrupts secretory vesicles in vitro and in vivo in transgenic mice.
-н: McGuinness, L, зэрэг
Хэвлэсэн: (2003)

Characterizing deformability and surface friction of cancer cells
-н: Byun, Sangwon, зэрэг
Хэвлэсэн: (2014)

A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis
-н: Reticker-Flynn, Nathan E., зэрэг
Хэвлэсэн: (2014)

Hypophosphatemic rickets is associated with disruption of mineral orientation at the nanoscale in the flat scapula bones of rachitic mice with development
-н: Karunaratne, A, зэрэг
Хэвлэсэн: (2012)

Hypophosphatemic rickets is associated with disruption of mineral orientation at the nanoscale in the flat scapula bones of rachitic mice with development.
-н: Karunaratne, A, зэрэг
Хэвлэсэн: (2012)

Managing innovation in the real estate industry : a theory of disruptive innovations
-н: Navasargian, Andre, 1975-, зэрэг
Хэвлэсэн: (2006)

Intercepting Pancreatic Cancer: Our Dream Teamʼs Resolve to Stop Pancreatic Cancer
-н: Jacks, Tyler E
Хэвлэсэн: (2020)

Chromatin Signature Reveals over a Thousand Highly Conserved Large Non-Coding Rnas in Mammals
-н: Guttman, Mitchell, зэрэг
Хэвлэсэн: (2010)

EVALUASI BESARAN ALOKASI DAK BIDANG KESEHATAN SUBBIDANG PELAYANAN KEFARMASIAN TAHUN 2011 - 2012
-н: , Risca Ardyaningtyas, зэрэг
Хэвлэсэн: (2014)

Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.
-н: Lavery, G, зэрэг
Хэвлэсэн: (2012)

Dynamics of disruption and recovery in air transportation networks
-н: Li, Max Z., зэрэг
Хэвлэсэн: (2022)

Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier
-н: Hagen, Susan J., зэрэг
Хэвлэсэн: (2018)

7.013 Introductory Biology, Spring 2006
-н: Sive, Hazel, зэрэг
Хэвлэсэн: (2019)

Imaging Primary Lung Cancers in Mice to Study Radiation Biology
-н: Kirsch, David G., зэрэг
Хэвлэсэн: (2016)

Disruption of the Broadcast
-н: Packer, Randall
Хэвлэсэн: (2017)

Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass
-н: Cantley, J, зэрэг
Хэвлэсэн: (2018)