The Role of Transcription in the Activation of a Drosophila Amplification Origin

The mechanisms that underlie metazoan DNA replication initiation, especially the connection between transcription and replication origin activation, are not well understood. To probe the role of transcription in origin activation, we exploited a specific replication origin in Drosophila melanogaster...

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Bibliographic Details
Main Authors: Hua, Brian, Li, Sharon, Orr-Weaver, Terry
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Genetics Society of America, The 2015
Online Access:http://hdl.handle.net/1721.1/96690
https://orcid.org/0000-0002-7934-111X
https://orcid.org/0000-0002-7580-3399