Catalytic Enantioselective Cyclization/Cross-Coupling with Alkyl Electrophiles
As part of our ongoing effort to expand the scope of cross-coupling reactions of alkyl electrophiles, we have pursued a strategy wherein the nucleophilic coupling partner includes a pendant olefin; after transmetalation by such a substrate, if β-migratory insertion proceeds faster than direct cross-...
Main Authors: | Cong, Huan, Fu, Gregory C. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2015
|
Online Access: | http://hdl.handle.net/1721.1/96696 |
Similar Items
-
Enantioselective alkylative cross-coupling of unactivated aromatic C–O electrophiles
by: Zishuo Zhang, et al.
Published: (2022-05-01) -
Nickel-catalyzed electrophiles-controlled enantioselective reductive arylative cyclization and enantiospecific reductive alkylative cyclization of 1,6-enynes
by: Wenfeng Liu, et al.
Published: (2024-02-01) -
Catalytic Enantioselective Cross-Couplings of Secondary Alkyl Electrophiles with Secondary Alkylmetal Nucleophiles: Negishi Reactions of Racemic Benzylic Bromides with Achiral Alkylzinc Reagents
by: Cordier, Christopher J., et al.
Published: (2013) -
Asymmetric Alkyl−Alkyl Cross-Couplings of Unactivated Secondary Alkyl Electrophiles: Stereoconvergent Suzuki Reactions of Racemic Acylated Halohydrins
by: Owston, Nathan A., et al.
Published: (2013) -
Enantioconvergent Cross-Couplings of Racemic Alkylmetal Reagents with Unactivated Secondary Alkyl Electrophiles: Catalytic Asymmetric Negishi α-Alkylations of N-Boc-Pyrrolidine
by: Cordier, Christopher J., et al.
Published: (2018)