Changes in Nucleosome Occupancy Associated with Metabolic Alterations in Aged Mammalian Liver

Changes in Nucleosome Occupancy Associated with Metabolic Alterations in Aged Mammalian Liver

Aging is accompanied by physiological impairments, which, in insulin-responsive tissues, including the liver, predispose individuals to metabolic disease. However, the molecular mechanisms underlying these changes remain largely unknown. Here, we analyze genome-wide profiles of RNA and chromatin org...

Полное описание

Библиографические подробности
Главные авторы:	Bochkis, Irina M., Przybylski, Dariusz, Chen, Jennifer, Regev, Aviv
Другие авторы:	Harvard University--MIT Division of Health Sciences and Technology
Формат:	Статья
Язык:	en_US
Опубликовано:	Elsevier B.V. 2015
Online-ссылка:	http://hdl.handle.net/1721.1/96715 https://orcid.org/0000-0001-8567-2049 https://orcid.org/0000-0002-6664-2597

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