Changes in Nucleosome Occupancy Associated with Metabolic Alterations in Aged Mammalian Liver
Aging is accompanied by physiological impairments, which, in insulin-responsive tissues, including the liver, predispose individuals to metabolic disease. However, the molecular mechanisms underlying these changes remain largely unknown. Here, we analyze genome-wide profiles of RNA and chromatin org...
Main Authors: | Bochkis, Irina M., Przybylski, Dariusz, Chen, Jennifer, Regev, Aviv |
---|---|
Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier B.V.
2015
|
Online Access: | http://hdl.handle.net/1721.1/96715 https://orcid.org/0000-0001-8567-2049 https://orcid.org/0000-0002-6664-2597 |
Similar Items
-
A quantitative framework for characterizing the evolutionary history of mammalian gene expression
by: Chen, Jenny (Jennifer), et al.
Published: (2020) -
Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing
by: Li, Carman Man-Chung, et al.
Published: (2021) -
The Role of Nucleosome Positioning in the Evolution of Gene Regulation
by: Tsankov, Alexander M., et al.
Published: (2010) -
A multimodal cell census and atlas of the mammalian primary motor cortex
by: Regev, Aviv
Published: (2023) -
Decoding human fetal liver haematopoiesis
by: Regev, Aviv
Published: (2022)