A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
The lysosome plays a key role in cellular homeostasis by controlling both cellular clearance and energy production to respond to environmental cues. However, the mechanisms mediating lysosomal adaptation are largely unknown. Here, we show that the Transcription Factor EB (TFEB), a master regulator o...
| Main Authors: | , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
EMBRO Press
2015
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| Online Access: | http://hdl.handle.net/1721.1/96733 https://orcid.org/0000-0002-1446-7256 |