Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
The mechanistic target of rapamycin complex 1 (mTORC1) protein kinase is a master growth regulator that responds to multiple environmental cues. Amino acids stimulate, in a Rag-, Ragulator-, and vacuolar adenosine triphosphatase–dependent fashion, the translocation of mTORC1 to the lysosomal surface...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Association for the Advancement of Science (AAAS)
2015
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| Online Access: | http://hdl.handle.net/1721.1/96751 https://orcid.org/0000-0003-4642-3706 https://orcid.org/0000-0002-9535-7664 https://orcid.org/0000-0002-4227-5163 https://orcid.org/0000-0001-6366-7986 https://orcid.org/0000-0002-1446-7256 https://orcid.org/0000-0001-9388-1633 |