The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera
Previous studies have reported that chromosome synteny in Lepidoptera has been well conserved, yet the number of haploid chromosomes varies widely from 5 to 223. Here we report the genome (393 Mb) of the Glanville fritillary butterfly (Melitaea cinxia; Nymphalidae), a widely recognized model species...
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| Format: | Article |
| Language: | en_US |
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Nature Publishing Group
2015
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| Online Access: | http://hdl.handle.net/1721.1/96778 |
| _version_ | 1811088625619697664 |
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| author | Waterhouse, Robert M. |
| author2 | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
| author_facet | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Waterhouse, Robert M. |
| author_sort | Waterhouse, Robert M. |
| collection | MIT |
| description | Previous studies have reported that chromosome synteny in Lepidoptera has been well conserved, yet the number of haploid chromosomes varies widely from 5 to 223. Here we report the genome (393 Mb) of the Glanville fritillary butterfly (Melitaea cinxia; Nymphalidae), a widely recognized model species in metapopulation biology and eco-evolutionary research, which has the putative ancestral karyotype of n=31. Using a phylogenetic analyses of Nymphalidae and of other Lepidoptera, combined with orthologue-level comparisons of chromosomes, we conclude that the ancestral lepidopteran karyotype has been n=31 for at least 140 My. We show that fusion chromosomes have retained the ancestral chromosome segments and very few rearrangements have occurred across the fusion sites. The same, shortest ancestral chromosomes have independently participated in fusion events in species with smaller karyotypes. The short chromosomes have higher rearrangement rate than long ones. These characteristics highlight distinctive features of the evolutionary dynamics of butterflies and moths. |
| first_indexed | 2024-09-23T14:04:57Z |
| format | Article |
| id | mit-1721.1/96778 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T14:04:57Z |
| publishDate | 2015 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/967782022-10-01T19:03:11Z The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera Waterhouse, Robert M. Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Waterhouse, Robert M. Previous studies have reported that chromosome synteny in Lepidoptera has been well conserved, yet the number of haploid chromosomes varies widely from 5 to 223. Here we report the genome (393 Mb) of the Glanville fritillary butterfly (Melitaea cinxia; Nymphalidae), a widely recognized model species in metapopulation biology and eco-evolutionary research, which has the putative ancestral karyotype of n=31. Using a phylogenetic analyses of Nymphalidae and of other Lepidoptera, combined with orthologue-level comparisons of chromosomes, we conclude that the ancestral lepidopteran karyotype has been n=31 for at least 140 My. We show that fusion chromosomes have retained the ancestral chromosome segments and very few rearrangements have occurred across the fusion sites. The same, shortest ancestral chromosomes have independently participated in fusion events in species with smaller karyotypes. The short chromosomes have higher rearrangement rate than long ones. These characteristics highlight distinctive features of the evolutionary dynamics of butterflies and moths. Marie Curie International Fellowship (PIOF-GA-2011-303312) 2015-04-24T13:30:30Z 2015-04-24T13:30:30Z 2014-09 2014-04 Article http://purl.org/eprint/type/JournalArticle 2041-1723 http://hdl.handle.net/1721.1/96778 Ahola, Virpi, Rainer Lehtonen, Panu Somervuo, Leena Salmela, Patrik Koskinen, Pasi Rastas, Niko Valimaki, et al. “The Glanville Fritillary Genome Retains an Ancient Karyotype and Reveals Selective Chromosomal Fusions in Lepidoptera.” Nature Communications 5 (September 5, 2014): 4737. en_US http://dx.doi.org/10.1038/ncomms5737 Nature Communications Creative Commons Attribution http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Nature Publishing Group Nature Publishing Group |
| spellingShingle | Waterhouse, Robert M. The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera |
| title | The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera |
| title_full | The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera |
| title_fullStr | The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera |
| title_full_unstemmed | The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera |
| title_short | The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera |
| title_sort | glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in lepidoptera |
| url | http://hdl.handle.net/1721.1/96778 |
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