Evaluating the sensitivity of hybridization-based epigenotyping using a methyl binding domain protein

Hypermethylation of CpG islands in gene promoter regions has been shown to be a predictive biomarker for certain diseases. Most current methods for methylation profiling are not well-suited for clinical analysis. Here, we report the development of an inexpensive device and an epigenotyping assay wit...

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Bibliographic Details
Main Authors: Shatova, Tatyana A., Lee, Jungkyu K., Kaastrup, Kaja, Heimer, Brandon Walter, Sikes, Hadley
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2015
Online Access:http://hdl.handle.net/1721.1/96893
https://orcid.org/0000-0003-1720-0183
https://orcid.org/0000-0002-7096-138X

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