Simple battery armor to protect against gastrointestinal injury from accidental ingestion
Inadvertent battery ingestion in children and the associated morbidity and mortality results in thousands of emergency room visits every year. Given the risk for serious electrochemical burns within hours of ingestion, the current standard of care for the treatment of batteries in the esophagus is e...
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| Format: | Article |
| Language: | en_US |
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National Academy of Sciences (U.S.)
2015
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| Online Access: | http://hdl.handle.net/1721.1/96898 https://orcid.org/0000-0002-4260-2785 https://orcid.org/0000-0003-4255-0492 |
| _version_ | 1826212468454588416 |
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| author | Laulicht, Bryan E. Deshpande, Vikram Karp, Jeffrey Michael Langer, Robert S Traverso, Carlo Giovanni |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Laulicht, Bryan E. Deshpande, Vikram Karp, Jeffrey Michael Langer, Robert S Traverso, Carlo Giovanni |
| author_sort | Laulicht, Bryan E. |
| collection | MIT |
| description | Inadvertent battery ingestion in children and the associated morbidity and mortality results in thousands of emergency room visits every year. Given the risk for serious electrochemical burns within hours of ingestion, the current standard of care for the treatment of batteries in the esophagus is emergent endoscopic removal. Safety standards now regulate locked battery compartments in toys, which have resulted in a modest reduction in inadvertent battery ingestion; specifically, 3,461 ingestions were reported in 2009, and 3,366 in 2013. Aside from legislation, minimal technological development has taken place at the level of the battery to limit injury. We have constructed a waterproof, pressure-sensitive coating, harnessing a commercially available quantum tunneling composite. Quantum tunneling composite coated (QTCC) batteries are nonconductive in the low-pressure gastrointestinal environment yet conduct within the higher pressure of standard battery housings. Importantly, this coating technology enables most battery-operated equipment to be powered without modification. If these new batteries are swallowed, they limit the external electrolytic currents responsible for tissue injury. We demonstrate in a large-animal model a significant decrease in tissue injury with QTCC batteries compared with uncoated control batteries. In summary, here we describe a facile approach to increasing the safety of batteries by minimizing the risk for electrochemical burn if the batteries are inadvertently ingested, without the need for modification of most battery-powered devices. |
| first_indexed | 2024-09-23T15:22:01Z |
| format | Article |
| id | mit-1721.1/96898 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:22:01Z |
| publishDate | 2015 |
| publisher | National Academy of Sciences (U.S.) |
| record_format | dspace |
| spelling | mit-1721.1/968982022-10-02T02:28:39Z Simple battery armor to protect against gastrointestinal injury from accidental ingestion Laulicht, Bryan E. Deshpande, Vikram Karp, Jeffrey Michael Langer, Robert S Traverso, Carlo Giovanni Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Chemical Engineering Koch Institute for Integrative Cancer Research at MIT Laulicht, Bryan E. Traverso, Gio Langer, Robert Karp, Jeffrey Michael Inadvertent battery ingestion in children and the associated morbidity and mortality results in thousands of emergency room visits every year. Given the risk for serious electrochemical burns within hours of ingestion, the current standard of care for the treatment of batteries in the esophagus is emergent endoscopic removal. Safety standards now regulate locked battery compartments in toys, which have resulted in a modest reduction in inadvertent battery ingestion; specifically, 3,461 ingestions were reported in 2009, and 3,366 in 2013. Aside from legislation, minimal technological development has taken place at the level of the battery to limit injury. We have constructed a waterproof, pressure-sensitive coating, harnessing a commercially available quantum tunneling composite. Quantum tunneling composite coated (QTCC) batteries are nonconductive in the low-pressure gastrointestinal environment yet conduct within the higher pressure of standard battery housings. Importantly, this coating technology enables most battery-operated equipment to be powered without modification. If these new batteries are swallowed, they limit the external electrolytic currents responsible for tissue injury. We demonstrate in a large-animal model a significant decrease in tissue injury with QTCC batteries compared with uncoated control batteries. In summary, here we describe a facile approach to increasing the safety of batteries by minimizing the risk for electrochemical burn if the batteries are inadvertently ingested, without the need for modification of most battery-powered devices. National Institutes of Health (U.S.) (Grant DE013023) National Institutes of Health (U.S.) (Grant EB000244) National Institutes of Health (U.S.) (Grant GM086433) National Institutes of Health (U.S.) (Grant T32 DK 7191-38) 2015-05-04T15:30:46Z 2015-05-04T15:30:46Z 2014-11 2014-08 Article http://purl.org/eprint/type/JournalArticle 0027-8424 1091-6490 http://hdl.handle.net/1721.1/96898 Laulicht, Bryan, Giovanni Traverso, Vikram Deshpande, Robert Langer, and Jeffrey M. Karp. “Simple Battery Armor to Protect Against Gastrointestinal Injury from Accidental Ingestion.” Proceedings of the National Academy of Sciences 111, no. 46 (November 3, 2014): 16490–16495. https://orcid.org/0000-0002-4260-2785 https://orcid.org/0000-0003-4255-0492 en_US http://dx.doi.org/10.1073/pnas.1418423111 Proceedings of the National Academy of Sciences Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf National Academy of Sciences (U.S.) National Academy of Sciences (U.S.) |
| spellingShingle | Laulicht, Bryan E. Deshpande, Vikram Karp, Jeffrey Michael Langer, Robert S Traverso, Carlo Giovanni Simple battery armor to protect against gastrointestinal injury from accidental ingestion |
| title | Simple battery armor to protect against gastrointestinal injury from accidental ingestion |
| title_full | Simple battery armor to protect against gastrointestinal injury from accidental ingestion |
| title_fullStr | Simple battery armor to protect against gastrointestinal injury from accidental ingestion |
| title_full_unstemmed | Simple battery armor to protect against gastrointestinal injury from accidental ingestion |
| title_short | Simple battery armor to protect against gastrointestinal injury from accidental ingestion |
| title_sort | simple battery armor to protect against gastrointestinal injury from accidental ingestion |
| url | http://hdl.handle.net/1721.1/96898 https://orcid.org/0000-0002-4260-2785 https://orcid.org/0000-0003-4255-0492 |
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