Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain

Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain

Metastases represent the most common brain tumors in adults. Surgical resection alone results in 45% recurrence and is usually accompanied by radiation and chemotherapy. Adequate chemotherapy delivery to the CNS is hindered by the blood–brain barrier. Efforts at delivering chemotherapy locally to gl...

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Bibliographic Details
Main Authors: Upadhyay, Urvashi M., Tyler, Betty, Patta, Yoda, Wicks, Robert, Scott, Alexander, Masi, Byron, Hwang, Lee, Grossman, Rachel, Brem, Henry, Cima, Michael J., Langer, Robert S, Spencer, Kevin C
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/96952
https://orcid.org/0000-0003-2379-6139
https://orcid.org/0000-0002-7963-8706
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/96952
https://orcid.org/0000-0003-2379-6139
https://orcid.org/0000-0002-7963-8706
https://orcid.org/0000-0003-4255-0492

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