Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain
Metastases represent the most common brain tumors in adults. Surgical resection alone results in 45% recurrence and is usually accompanied by radiation and chemotherapy. Adequate chemotherapy delivery to the CNS is hindered by the blood–brain barrier. Efforts at delivering chemotherapy locally to gl...
Main Authors: | Upadhyay, Urvashi M., Tyler, Betty, Patta, Yoda, Wicks, Robert, Scott, Alexander, Masi, Byron, Hwang, Lee, Grossman, Rachel, Brem, Henry, Cima, Michael J., Langer, Robert S, Spencer, Kevin C |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2015
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Online Access: | http://hdl.handle.net/1721.1/96952 https://orcid.org/0000-0003-2379-6139 https://orcid.org/0000-0002-7963-8706 https://orcid.org/0000-0003-4255-0492 |
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