Excess cholesterol induces mouse egg activation and may cause female infertility

Excess cholesterol induces mouse egg activation and may cause female infertility

The HDL receptor scavenger receptor, class B type I (SR-BI) controls the structure and fate of plasma HDL. Female SR-BI KO mice are infertile, apparently because of their abnormal cholesterol-enriched HDL particles. We examined the growth and meiotic progression of SR-BI KO oocytes and found that th...

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Bibliographic Details
Main Authors: Yesilaltay, Ayce, Dokshin, Gregoriy A., Busso, Dolores, Wang, Li, Galiani, Dalia, Vasile, Eliza, Quilaqueo, Linda, Orellana, Juan Andrés, Shalgi, Ruth, Dekel, Nava, Albertini, David F., Rigotti, Attilio, Krieger, Monty, Walzer, Dalia F., Page, David C, Chavarria, Tony E
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/96953
https://orcid.org/0000-0003-2585-0610
https://orcid.org/0000-0001-9920-3411
https://orcid.org/0000-0003-4541-5181
https://orcid.org/0000-0001-9905-5316

Internet

http://hdl.handle.net/1721.1/96953
https://orcid.org/0000-0003-2585-0610
https://orcid.org/0000-0001-9920-3411
https://orcid.org/0000-0003-4541-5181
https://orcid.org/0000-0001-9905-5316

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