The role of DNA methylation in directing the functional organization of the cancer epigenome

The role of DNA methylation in directing the functional organization of the cancer epigenome

The holistic role of DNA methylation in the organization of the cancer epigenome is not well understood. Here we perform a comprehensive, high-resolution analysis of chromatin structure to compare the landscapes of HCT116 colon cancer cells and a DNA methylation-deficient derivative. The NOMe-seq ac...

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Bibliographic Details
Main Authors: Lay, Fides D., Liu, Yaping, Kelly, Theresa K., Witt, Heather, Farnham, Peggy J., Jones, Peter A., Berman, Benjamin P.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2015
Online Access:http://hdl.handle.net/1721.1/97064
https://orcid.org/0000-0003-4165-7693

Internet

http://hdl.handle.net/1721.1/97064
https://orcid.org/0000-0003-4165-7693

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