Tumor Angiogenesis in the Absence of Fibronectin or Its Cognate Integrin Receptors
Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in the extracellular matrix has been targeted as a possible means of blocking tumor angiogenesis and tumor growth. However, clinical trials of blocking antibodies and peptides have been disappointing des...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2015
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| Online Access: | http://hdl.handle.net/1721.1/97114 https://orcid.org/0000-0001-7603-8396 |