Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

Albumin is the most abundant protein in human serum and drugs that are administered intravenously inevitably interact with it. We present here a series of platinum(IV) prodrugs designed specifically to enhance interaction with human serum albumin (HSA) for drug delivery. This goal is achieved by asy...

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Bibliographic Details
Main Authors: Suntharalingam, Kogularamanan, Yoo, Hyunsuk, Lin, Wei, Brooks, Jamar G., Lippard, Stephen J., Zheng, Yaorong, Johnstone, Timothy
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/97217
https://orcid.org/0000-0002-2693-4982

Internet

http://hdl.handle.net/1721.1/97217
https://orcid.org/0000-0002-2693-4982

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