Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery
Albumin is the most abundant protein in human serum and drugs that are administered intravenously inevitably interact with it. We present here a series of platinum(IV) prodrugs designed specifically to enhance interaction with human serum albumin (HSA) for drug delivery. This goal is achieved by asy...
Main Authors: | Suntharalingam, Kogularamanan, Yoo, Hyunsuk, Lin, Wei, Brooks, Jamar G., Lippard, Stephen J., Zheng, Yaorong, Johnstone, Timothy |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2015
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Online Access: | http://hdl.handle.net/1721.1/97217 https://orcid.org/0000-0002-2693-4982 |
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