Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels

Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels

Arteriovenous (AV) malformation (AVM) is a devastating condition characterized by focal lesions of enlarged, tangled vessels that shunt blood from arteries directly to veins. AVMs can form anywhere in the body and can cause debilitating ischemia and life-threatening hemorrhagic stroke. The mechanism...

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Bibliographic Details
Main Authors:	Kim, Tyson N., Huang, Lawrence, Nielsen, Corinne M., Lawton, Michael T., Adams, Ralf H., Schaffer, Chris B., Wang, Rong A., Murphy, Patrick Andries
Other Authors:	Koch Institute for Integrative Cancer Research at MIT
Format:	Article
Language:	en_US
Published:	National Academy of Sciences (U.S.) 2015
Online Access:	http://hdl.handle.net/1721.1/97434

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