Versatile RNA Interference Nanoplatform for Systemic Delivery of RNAs

Versatile RNA Interference Nanoplatform for Systemic Delivery of RNAs

Development of nontoxic, tumor-targetable, and potent in vivo RNA delivery systems remains an arduous challenge for clinical application of RNAi therapeutics. Herein, we report a versatile RNAi nanoplatform based on tumor-targeted and pH-responsive nanoformulas (NFs). The NF was engineered by combin...

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Bibliographic Details
Main Authors: Choi, Ki Young, Silvestre, Oscar F., Huang, Xinglu, Min, Kyung Hyun, Howard, Gregory P., Hida, Naoki, Jin, Albert J., Carvajal, Nicole, Lee, Sang Wook, Hong, Jong-In, Chen, Xiaoyuan
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/97479
https://orcid.org/0000-0002-8848-7559

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