Visualizing KcsA Conformational Changes upon Ion Binding by Infrared Spectroscopy and Atomistic Modeling

Visualizing KcsA Conformational Changes upon Ion Binding by Infrared Spectroscopy and Atomistic Modeling

The effect of ion binding in the selectivity filter of the potassium channel KcsA is investigated by combining amide I Fourier-transform infrared spectroscopy with structure-based spectral modeling. Experimental difference IR spectra between K[superscript +]-bound KcsA and Na[superscript +]-bound Kc...

Full description

Bibliographic Details
Main Authors: Stevenson, Paul, Baiz, Carlos R., Akerboom, Jasper, Tokmakoff, Andrei, Vaziri, Alipasha, Gotz, Christoph
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/97497
https://orcid.org/0000-0002-6616-0328

Internet

http://hdl.handle.net/1721.1/97497
https://orcid.org/0000-0002-6616-0328

Similar Items