RNA-seq: impact of RNA degradation on transcript quantification

RNA-seq: impact of RNA degradation on transcript quantification

Background The use of low quality RNA samples in whole-genome gene expression profiling remains controversial. It is unclear if transcript degradation in low quality RNA samples occurs uniformly, in which case the effects of degradation can be corrected via data normalization, or whether different...

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Bibliographic Details
Main Authors:	Gallego Romero, Irene, Tung, Jenny, Gilad, Yoav, Pai, Athma A.
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	English
Published:	BioMed Central 2015
Online Access:	http://hdl.handle.net/1721.1/97557 https://orcid.org/0000-0002-7995-9948

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