A DNA/HDAC dual-targeting drug CY190602 with significantly enhanced anticancer potency

A DNA/HDAC dual-targeting drug CY190602 with significantly enhanced anticancer potency

Genotoxic drugs constitute a major treatment modality for human cancers; however, cancer cells' intrinsic DNA repair capability often increases the threshold of lethality and renders these drugs ineffective. The emerging roles of HDACs in DNA repair provide new opportunities for improving tradi...

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Bibliographic Details
Main Authors: Hemann, Michael, Liu, Chuan, Ding, Hongyu, Li, Xiaoxi, Pallasch, Christian, Hong, Liya, Guo, Dianwu, Chen, Yi, Wang, Difei, Wang, Wei, Wang, Yajie, Jiang, Hai, 1979-
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Wiley Blackwell 2015
Online Access:http://hdl.handle.net/1721.1/97593

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