Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses
To aid understanding we use idealized pulse waveforms. The pulses are trapezoidal, with linear ramps that define the rise and fall times, and a flat peak field strength. Again for simplicity, we label a pulse duration by the duration from start to end. The model can also be used with digitized exper...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Other |
| Language: | en_US |
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Springer-Verlag
2015
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| Online Access: | http://hdl.handle.net/1721.1/97707 https://orcid.org/0000-0002-9016-5962 |
| _version_ | 1826214097465638912 |
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| author | Son, Reuben S. Smith, Kyle C. Gowrishankar, Thiruvallur R. Vernier, P. Thomas Weaver, James C |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Son, Reuben S. Smith, Kyle C. Gowrishankar, Thiruvallur R. Vernier, P. Thomas Weaver, James C |
| author_sort | Son, Reuben S. |
| collection | MIT |
| description | To aid understanding we use idealized pulse waveforms. The pulses are trapezoidal, with linear ramps that define the rise and fall times, and a flat peak field strength. Again for simplicity, we label a pulse duration by the duration from start to end. The model can also be used with digitized experimental waveforms. Significant averaging occurs in computing cumulative solute transport, which supports our use of idealized waveforms for understanding basic behavior. There is underlying spatial averaging of U[subscript m(t) behavior that is are distributed over several hundred transmembrane node-pairs, and also integrating the solute transport rates with respect to time. |
| first_indexed | 2024-09-23T15:59:27Z |
| format | Other |
| id | mit-1721.1/97707 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:59:27Z |
| publishDate | 2015 |
| publisher | Springer-Verlag |
| record_format | dspace |
| spelling | mit-1721.1/977072022-10-02T05:34:42Z Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses Son, Reuben S. Smith, Kyle C. Gowrishankar, Thiruvallur R. Vernier, P. Thomas Weaver, James C Massachusetts Institute of Technology. Institute for Medical Engineering & Science Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Son, Reuben S. Smith, Kyle C. Gowrishankar, Thiruvallur R. Weaver, James C. To aid understanding we use idealized pulse waveforms. The pulses are trapezoidal, with linear ramps that define the rise and fall times, and a flat peak field strength. Again for simplicity, we label a pulse duration by the duration from start to end. The model can also be used with digitized experimental waveforms. Significant averaging occurs in computing cumulative solute transport, which supports our use of idealized waveforms for understanding basic behavior. There is underlying spatial averaging of U[subscript m(t) behavior that is are distributed over several hundred transmembrane node-pairs, and also integrating the solute transport rates with respect to time. 2015-07-07T19:59:40Z 2015-07-07T19:59:40Z 2014-07 2014-04 Other http://purl.org/eprint/type/JournalItem 0022-2631 1432-1424 http://hdl.handle.net/1721.1/97707 Son, Reuben S., Kyle C. Smith, Thiruvallur R. Gowrishankar, P. Thomas Vernier, and James C. Weaver. “Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses.” J Membrane Biol 247, no. 12 (July 22, 2014). https://orcid.org/0000-0002-9016-5962 en_US http://static-content.springer.com/esm/art%3A10.1007%2Fs00232-014-9699-z/MediaObjects/232_2014_9699_MOESM1_ESM.pdf http://hdl.handle.net/1721.1/96516 http://hdl.handle.net/1721.1/97734 Journal of Membrane Biology Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Springer-Verlag Gowrishankar |
| spellingShingle | Son, Reuben S. Smith, Kyle C. Gowrishankar, Thiruvallur R. Vernier, P. Thomas Weaver, James C Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses |
| title | Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses |
| title_full | Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses |
| title_fullStr | Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses |
| title_full_unstemmed | Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses |
| title_short | Supplemental Information for Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses |
| title_sort | supplemental information for basic features of a cell electroporation model illustrative behavior for two very different pulses |
| url | http://hdl.handle.net/1721.1/97707 https://orcid.org/0000-0002-9016-5962 |
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