Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil
Nanotechnology may offer fast and effective solutions for environmental clean-up. Herein, amphiphilic diblock copolymers are used to develop a platform of photosensitive core-shell nanoparticles. Irradiation with ultraviolet light removes the protective layer responsible for colloidal stability; as...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | en_US |
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Nature Publishing Group
2015
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| Online Access: | http://hdl.handle.net/1721.1/97882 https://orcid.org/0000-0003-4255-0492 |
| _version_ | 1811088801542438912 |
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| author | Brandl, Ferdinand Bertrand, Nicolas Lima, Eliana Martins Langer, Robert S |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Brandl, Ferdinand Bertrand, Nicolas Lima, Eliana Martins Langer, Robert S |
| author_sort | Brandl, Ferdinand |
| collection | MIT |
| description | Nanotechnology may offer fast and effective solutions for environmental clean-up. Herein, amphiphilic diblock copolymers are used to develop a platform of photosensitive core-shell nanoparticles. Irradiation with ultraviolet light removes the protective layer responsible for colloidal stability; as a result, the nanoparticles are rapidly and irreversibly converted to macroscopic aggregates. The associated phase separation allows measuring the partitioning of small molecules between the aqueous phase and nanoparticles; data suggests that interactions are enhanced by decreasing the particle size. Adsorption onto nanoparticles can be exploited to efficiently remove hydrophobic pollutants from water and contaminated soil. Preliminary in vivo experiments suggest that treatment with photocleavable nanoparticles can significantly reduce the teratogenicity of bisphenol A, triclosan and 17α-ethinyl estradiol without generating obviously toxic byproducts. Small-scale pilot experiments on wastewater, thermal printing paper and contaminated soil demonstrate the applicability of the approach. |
| first_indexed | 2024-09-23T14:07:46Z |
| format | Article |
| id | mit-1721.1/97882 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T14:07:46Z |
| publishDate | 2015 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/978822022-09-28T18:41:15Z Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil Brandl, Ferdinand Bertrand, Nicolas Lima, Eliana Martins Langer, Robert S Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Chemical Engineering Koch Institute for Integrative Cancer Research at MIT Brandl, Ferdinand Bertrand, Nicolas Langer, Robert Nanotechnology may offer fast and effective solutions for environmental clean-up. Herein, amphiphilic diblock copolymers are used to develop a platform of photosensitive core-shell nanoparticles. Irradiation with ultraviolet light removes the protective layer responsible for colloidal stability; as a result, the nanoparticles are rapidly and irreversibly converted to macroscopic aggregates. The associated phase separation allows measuring the partitioning of small molecules between the aqueous phase and nanoparticles; data suggests that interactions are enhanced by decreasing the particle size. Adsorption onto nanoparticles can be exploited to efficiently remove hydrophobic pollutants from water and contaminated soil. Preliminary in vivo experiments suggest that treatment with photocleavable nanoparticles can significantly reduce the teratogenicity of bisphenol A, triclosan and 17α-ethinyl estradiol without generating obviously toxic byproducts. Small-scale pilot experiments on wastewater, thermal printing paper and contaminated soil demonstrate the applicability of the approach. Germany. Federal Ministry of Education and Research (Max Planck Society for the Advancement of Science Research Award) National Cancer Institute (U.S.) (Grant U54-CA151884) National Heart, Lung, and Blood Institute (Program of Excellence in Nanotechnology Award Contract HHSN268201000045C) Prostate Cancer Foundation (Award in Nanotherapeutics) Canadian Institutes of Health Research (Postdoctoral Fellowship) 2015-07-22T16:21:10Z 2015-07-22T16:21:10Z 2015-07 2015-02 Article http://purl.org/eprint/type/JournalArticle 2041-1723 http://hdl.handle.net/1721.1/97882 Brandl, Ferdinand, Nicolas Bertrand, Eliana Martins Lima, and Robert Langer. “Nanoparticles with Photoinduced Precipitation for the Extraction of Pollutants from Water and Soil.” Nature Communications 6 (July 21, 2015): 7765. © 2015 Macmillan Publishers Limited https://orcid.org/0000-0003-4255-0492 en_US http://dx.doi.org/10.1038/ncomms8765 Nature Communications Creative Commons Attribution http://creativecommons.org/licenses/by/4.0/ application/pdf Nature Publishing Group Nature |
| spellingShingle | Brandl, Ferdinand Bertrand, Nicolas Lima, Eliana Martins Langer, Robert S Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil |
| title | Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil |
| title_full | Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil |
| title_fullStr | Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil |
| title_full_unstemmed | Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil |
| title_short | Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil |
| title_sort | nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil |
| url | http://hdl.handle.net/1721.1/97882 https://orcid.org/0000-0003-4255-0492 |
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