Alternative Splicing of Endothelial Fibronectin Is Induced by Disturbed Hemodynamics and Protects Against Hemorrhage of the Vessel Wall
Objective—Abnormally low-flow conditions, sensed by the arterial endothelium, promote aneurysm rupture. Fibronectin (FN) is among the most abundant extracellular matrix proteins and is strongly upregulated in human aneurysms, suggesting a possible role in disease progression. Altered FN splicing can...
| Main Authors: | , |
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| Format: | Article |
| Language: | en_US |
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Ovid Technologies (Wolters Kluwer) -American Heart Association
2015
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| Online Access: | http://hdl.handle.net/1721.1/98094 https://orcid.org/0000-0001-7603-8396 |