Inhibiting the Activity of CA1 Hippocampal Neurons Prevents the Recall of Contextual Fear Memory in Inducible ArchT Transgenic Mice

Inhibiting the Activity of CA1 Hippocampal Neurons Prevents the Recall of Contextual Fear Memory in Inducible ArchT Transgenic Mice

The optogenetic manipulation of light-activated ion-channels/pumps (i.e., opsins) can reversibly activate or suppress neuronal activity with precise temporal control. Therefore, optogenetic techniques hold great potential to establish causal relationships between specific neuronal circuits and their...

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Bibliographic Details
Main Authors: Sakaguchi, Masanori, Kim, Karam, Yu, Lily Mae Yee, Hashikawa, Yoshiko, Sekine, Yukiko, Okumura, Yuki, Kawano, Masako, Hayashi, Masanobu, Kumar, Deependra, McHugh, Thomas J., Hayashi, Yasunori, Boyden, Edward
Other Authors: Massachusetts Institute of Technology. Media Laboratory
Format: Article
Language:en_US
Published: Public Library of Science 2015
Online Access:http://hdl.handle.net/1721.1/98168
https://orcid.org/0000-0002-0419-3351

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