Transmembrane tethering of synaptotagmin to synaptic vesicles controls multiple modes of neurotransmitter release
Synaptotagmin 1 (Syt1) is a synaptic vesicle integral membrane protein that regulates neurotransmitter release by activating fast synchronous fusion and suppressing slower asynchronous release. The cytoplasmic C2 domains of Syt1 interact with SNAREs and plasma membrane phospholipids in a Ca[superscr...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences (U.S.)
2015
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| Online Access: | http://hdl.handle.net/1721.1/98385 https://orcid.org/0000-0001-5576-2887 |