Representation of Accumulating Evidence for a Decision in Two Parietal Areas
Decisions are often made by accumulating evidence for and against the alternatives. The momentary evidence represented by sensory neurons is accumulated by downstream structures to form a decision variable, linking the evolving decision to the formation of a motor plan. When decisions are communicat...
| Main Authors: | , , |
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| Format: | Article |
| Language: | en_US |
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Society for Neuroscience
2015
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| Online Access: | http://hdl.handle.net/1721.1/98396 |
| _version_ | 1826209364433698816 |
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| author | de Lafuente, Victor Jazayeri, Mehrdad Shadlen, Michael N. |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences de Lafuente, Victor Jazayeri, Mehrdad Shadlen, Michael N. |
| author_sort | de Lafuente, Victor |
| collection | MIT |
| description | Decisions are often made by accumulating evidence for and against the alternatives. The momentary evidence represented by sensory neurons is accumulated by downstream structures to form a decision variable, linking the evolving decision to the formation of a motor plan. When decisions are communicated by eye movements, neurons in the lateral intraparietal area (LIP) represent the accumulation of evidence bearing on the potential targets for saccades. We now show that reach-related neurons from the medial intraparietal area (MIP) exhibit a gradual modulation of their firing rates consistent with the representation of an evolving decision variable. When decisions were communicated by saccades instead of reaches, decision-related activity was attenuated in MIP, whereas LIP neurons were active while monkeys communicated decisions by saccades or reaches. Thus, for decisions communicated by a hand movement, a parallel flow of sensory information is directed to parietal areas MIP and LIP during decision formation. |
| first_indexed | 2024-09-23T14:21:40Z |
| format | Article |
| id | mit-1721.1/98396 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T14:21:40Z |
| publishDate | 2015 |
| publisher | Society for Neuroscience |
| record_format | dspace |
| spelling | mit-1721.1/983962022-10-01T20:48:44Z Representation of Accumulating Evidence for a Decision in Two Parietal Areas de Lafuente, Victor Jazayeri, Mehrdad Shadlen, Michael N. Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT Jazayeri, Mehrdad Decisions are often made by accumulating evidence for and against the alternatives. The momentary evidence represented by sensory neurons is accumulated by downstream structures to form a decision variable, linking the evolving decision to the formation of a motor plan. When decisions are communicated by eye movements, neurons in the lateral intraparietal area (LIP) represent the accumulation of evidence bearing on the potential targets for saccades. We now show that reach-related neurons from the medial intraparietal area (MIP) exhibit a gradual modulation of their firing rates consistent with the representation of an evolving decision variable. When decisions were communicated by saccades instead of reaches, decision-related activity was attenuated in MIP, whereas LIP neurons were active while monkeys communicated decisions by saccades or reaches. Thus, for decisions communicated by a hand movement, a parallel flow of sensory information is directed to parietal areas MIP and LIP during decision formation. 2015-09-08T16:42:45Z 2015-09-08T16:42:45Z 2015-03 2014-12 Article http://purl.org/eprint/type/JournalArticle 0270-6474 1529-2401 http://hdl.handle.net/1721.1/98396 de Lafuente, V., M. Jazayeri, and M. N. Shadlen. “Representation of Accumulating Evidence for a Decision in Two Parietal Areas.” Journal of Neuroscience 35, no. 10 (March 11, 2015): 4306–18. en_US http://dx.doi.org/10.1523/jneurosci.2451-14.2015 Journal of Neuroscience Creative Commons Attribution http://creativecommons.org/licenses/by/4.0/ application/pdf Society for Neuroscience Society for Neuroscience |
| spellingShingle | de Lafuente, Victor Jazayeri, Mehrdad Shadlen, Michael N. Representation of Accumulating Evidence for a Decision in Two Parietal Areas |
| title | Representation of Accumulating Evidence for a Decision in Two Parietal Areas |
| title_full | Representation of Accumulating Evidence for a Decision in Two Parietal Areas |
| title_fullStr | Representation of Accumulating Evidence for a Decision in Two Parietal Areas |
| title_full_unstemmed | Representation of Accumulating Evidence for a Decision in Two Parietal Areas |
| title_short | Representation of Accumulating Evidence for a Decision in Two Parietal Areas |
| title_sort | representation of accumulating evidence for a decision in two parietal areas |
| url | http://hdl.handle.net/1721.1/98396 |
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