Steric clashes with bound OMP peptides activate the DegS stress-response protease
Escherichia coli senses envelope stress using a signaling cascade initiated when DegS cleaves a transmembrane inhibitor of a transcriptional activator for response genes. Each subunit of the DegS trimer contains a protease domain and a PDZ domain. During stress, unassembled outer-membrane proteins (...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences (U.S.)
2015
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| Online Access: | http://hdl.handle.net/1721.1/98399 https://orcid.org/0000-0002-1719-5399 |