Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

Splenic myelopoiesis provides a steady flow of leukocytes to inflamed tissues, and leukocytosis correlates with cardiovascular mortality. Yet regulation of hematopoietic stem cell (HSC) activity in the spleen is incompletely understood. Here, we show that red pulp vascular cell adhesion molecule 1 (...

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Bibliographic Details
Main Authors: Dutta, Partha, Hoyer, Friedrich Felix, Grigoryeva, Lubov S., Sager, Hendrik B., Leuschner, Florian, Courties, Gabriel, Borodovsky, Anna, Novobrantseva, Tatiana I., Ruda, Vera M., Fitzgerald, Kevin, Iwamoto, Yoshiko, Wojtkiewicz, Gregory, Sun, Yuan, Da Silva, Nicolas, Libby, Peter, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias, Anderson, Daniel Griffith
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Rockefeller University Press 2015
Online Access:http://hdl.handle.net/1721.1/98402
https://orcid.org/0000-0001-5629-4798

Internet

http://hdl.handle.net/1721.1/98402
https://orcid.org/0000-0001-5629-4798

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