A highly selective biosynthetic pathway to non-natural C[subscript 50] carotenoids assembled from moderately selective enzymes

Synthetic biology aspires to construct natural and non-natural pathways to useful compounds. However, pathways that rely on multiple promiscuous enzymes may branch, which might preclude selective production of the target compound. Here, we describe the assembly of a six-enzyme pathway in Escherichia...

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Bibliographic Details
Main Authors: Furubayashi, Maiko, Ikezumi, Mayu, Takaichi, Shinichi, Maoka, Takashi, Hemmi, Hisashi, Ogawa, Takuya, Saito, Kyoichi, Tobias, Alexander V, Umeno, Daisuke
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/98477
https://orcid.org/0000-0001-5215-523X