A highly selective biosynthetic pathway to non-natural C[subscript 50] carotenoids assembled from moderately selective enzymes
Synthetic biology aspires to construct natural and non-natural pathways to useful compounds. However, pathways that rely on multiple promiscuous enzymes may branch, which might preclude selective production of the target compound. Here, we describe the assembly of a six-enzyme pathway in Escherichia...
Main Authors: | Furubayashi, Maiko, Ikezumi, Mayu, Takaichi, Shinichi, Maoka, Takashi, Hemmi, Hisashi, Ogawa, Takuya, Saito, Kyoichi, Tobias, Alexander V, Umeno, Daisuke |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2015
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Online Access: | http://hdl.handle.net/1721.1/98477 https://orcid.org/0000-0001-5215-523X |
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