Regulation of heparanase expression in coronary artery disease in diabetic, hyperlipidemic swine

Objective Enzymatic degradation of the extracellular matrix is known to be powerful regulator of atherosclerosis. However, little is known about the enzymatic regulation of heparan sulfate proteoglycans (HSPGs) during the formation and progression of atherosclerotic plaques. Methods and results S...

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Main Authors: Baker, Aaron B., Chatzizisis, Yiannis S., Beigel, Roy, Jonas, Michael, Stone, Benjamin V., Coskun, Ahmet U., Maynard, Charles, Rogers, Campbell, Koskinas, Konstantinos C., Feldman, Charles L., Stone, Peter H., Edelman, Elazer R.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99184
https://orcid.org/0000-0002-7832-7156