Lack of Commensal Flora in H. pylori–Infected INS-GAS Mice Reduces Gastritis and Delays Intraepithelial Neoplasia

Lack of Commensal Flora in H. pylori–Infected INS-GAS Mice Reduces Gastritis and Delays Intraepithelial Neoplasia

Background & Aims Transgenic FVB/N insulin-gastrin (INS-GAS) mice have high circulating gastrin levels, and develop spontaneous atrophic gastritis and gastrointestinal intraepithelial neoplasia (GIN) with 80% prevalence 6 months after Helicobacter pylori infection. GIN is associated with gastri...

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Bibliographic Details
Main Authors: Lofgren, Jennifer L., Whary, Mark T., Ge, Zhongming, Muthupalani, Sureshkumar, Taylor, Nancy S., Mobley, Melissa W., Potter, Amanda, Varro, Andrea, Eibach, Daniel, Suerbaum, Sebastian, Wang, Timothy C., Fox, James G.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99201
https://orcid.org/0000-0001-9307-6116

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