Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions

Cryo-electron microscopy produces 3D density maps of molecular machines, which consist of various molecular components such as proteins and RNA. Segmentation of individual components in such maps is a challenging task, and is mostly accomplished interactively. We present an approach based on the imm...

Full description

Bibliographic Details
Main Authors: Pintilie, Grigore D., Zhang, Junjie, Goddard, Thomas D., Chiu, Wah, Gossard, David C.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99224
https://orcid.org/0000-0001-7706-6954

Similar Items