Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions
Cryo-electron microscopy produces 3D density maps of molecular machines, which consist of various molecular components such as proteins and RNA. Segmentation of individual components in such maps is a challenging task, and is mostly accomplished interactively. We present an approach based on the imm...
Main Authors: | Pintilie, Grigore D., Zhang, Junjie, Goddard, Thomas D., Chiu, Wah, Gossard, David C. |
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Other Authors: | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/99224 https://orcid.org/0000-0001-7706-6954 |
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