Materials by design: Merging proteins and music
Tailored materials with tunable properties are crucial for applications as biomaterials, for drug delivery, as functional coatings, or as lightweight composites. An emerging paradigm in designing such materials is the construction of hierarchical assemblies of simple building blocks into complex arc...
| Main Authors: | , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2015
|
| Online Access: | http://hdl.handle.net/1721.1/99227 https://orcid.org/0000-0002-4173-9659 |
| _version_ | 1826188592250093568 |
|---|---|
| author | Wong, Joyce Y. McDonald, John Taylor-Pinney, Micki Kaplan, David L. Spivak, David I Buehler, Markus J |
| author2 | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Wong, Joyce Y. McDonald, John Taylor-Pinney, Micki Kaplan, David L. Spivak, David I Buehler, Markus J |
| author_sort | Wong, Joyce Y. |
| collection | MIT |
| description | Tailored materials with tunable properties are crucial for applications as biomaterials, for drug delivery, as functional coatings, or as lightweight composites. An emerging paradigm in designing such materials is the construction of hierarchical assemblies of simple building blocks into complex architectures with superior properties. We review this approach in a case study of silk, a genetically programmable and processable biomaterial, which, in its natural role serves as a versatile protein fiber with hierarchical organization to provide structural support, prey procurement or protection of eggs. Through an abstraction of knowledge from the physical system, silk, to a mathematical model using category theory, we describe how the mechanism of spinning fibers from proteins can be translated into music through a process that assigns a set of rules that governs the construction of the system. This technique allows one to express the structure, mechanisms and properties of the ‘material’ in a very different domain, ‘music’. The integration of science and art through categorization of structure–property relationships presents a novel paradigm to create new bioinspired materials, through the translation of structures and mechanisms from distinct hierarchical systems and in the context of the limited number of building blocks that universally governs these systems. |
| first_indexed | 2024-09-23T08:02:04Z |
| format | Article |
| id | mit-1721.1/99227 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T08:02:04Z |
| publishDate | 2015 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/992272022-09-23T10:24:07Z Materials by design: Merging proteins and music Wong, Joyce Y. McDonald, John Taylor-Pinney, Micki Kaplan, David L. Spivak, David I Buehler, Markus J Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Massachusetts Institute of Technology. Department of Mathematics Massachusetts Institute of Technology. Laboratory for Atomistic and Molecular Mechanics Spivak, David I. Buehler, Markus J. Tailored materials with tunable properties are crucial for applications as biomaterials, for drug delivery, as functional coatings, or as lightweight composites. An emerging paradigm in designing such materials is the construction of hierarchical assemblies of simple building blocks into complex architectures with superior properties. We review this approach in a case study of silk, a genetically programmable and processable biomaterial, which, in its natural role serves as a versatile protein fiber with hierarchical organization to provide structural support, prey procurement or protection of eggs. Through an abstraction of knowledge from the physical system, silk, to a mathematical model using category theory, we describe how the mechanism of spinning fibers from proteins can be translated into music through a process that assigns a set of rules that governs the construction of the system. This technique allows one to express the structure, mechanisms and properties of the ‘material’ in a very different domain, ‘music’. The integration of science and art through categorization of structure–property relationships presents a novel paradigm to create new bioinspired materials, through the translation of structures and mechanisms from distinct hierarchical systems and in the context of the limited number of building blocks that universally governs these systems. National Institutes of Health (U.S.) (U01 EB014976) National Science Foundation (U.S.) (CAREER 0642545) National Science Foundation (U.S.) (CBET 1067093) United States. Office of Naval Research (PECASE N00014-10-1-0562) United States. Air Force Office of Scientific Research (FA9550-11-1-0199) 2015-10-13T18:03:36Z 2015-10-13T18:03:36Z 2012-11 2012-07 Article http://purl.org/eprint/type/JournalArticle 17480132 http://hdl.handle.net/1721.1/99227 Wong, Joyce Y., John McDonald, Micki Taylor-Pinney, David I. Spivak, David L. Kaplan, and Markus J. Buehler. “Materials by Design: Merging Proteins and Music.” Nano Today 7, no. 6 (December 2012): 488–495. https://orcid.org/0000-0002-4173-9659 en_US http://dx.doi.org/10.1016/j.nantod.2012.09.001 Nano Today Creative Commons Attribution-Noncommercial-NoDerivatives http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier MIT Web Domain |
| spellingShingle | Wong, Joyce Y. McDonald, John Taylor-Pinney, Micki Kaplan, David L. Spivak, David I Buehler, Markus J Materials by design: Merging proteins and music |
| title | Materials by design: Merging proteins and music |
| title_full | Materials by design: Merging proteins and music |
| title_fullStr | Materials by design: Merging proteins and music |
| title_full_unstemmed | Materials by design: Merging proteins and music |
| title_short | Materials by design: Merging proteins and music |
| title_sort | materials by design merging proteins and music |
| url | http://hdl.handle.net/1721.1/99227 https://orcid.org/0000-0002-4173-9659 |
| work_keys_str_mv | AT wongjoycey materialsbydesignmergingproteinsandmusic AT mcdonaldjohn materialsbydesignmergingproteinsandmusic AT taylorpinneymicki materialsbydesignmergingproteinsandmusic AT kaplandavidl materialsbydesignmergingproteinsandmusic AT spivakdavidi materialsbydesignmergingproteinsandmusic AT buehlermarkusj materialsbydesignmergingproteinsandmusic |