A physical mechanism to explain the delivery of chemical penetration enhancers into skin during transdermal sonophoresis — Insight into the observed synergism

The synergism between low-frequency sonophoresis (LFS) and chemical penetration enhancers (CPEs), especially surfactants, in transdermal enhancement has been investigated extensively since this phenomenon was first observed over a decade ago. In spite of the identifying that the origin of this syner...

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Bibliographic Details
Main Authors: Polat, Baris E., Deen, William M., Langer, Robert, Blankschtein, Daniel
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99235
https://orcid.org/0000-0001-5966-6462
https://orcid.org/0000-0002-7836-415X
https://orcid.org/0000-0003-4255-0492