A physical mechanism to explain the delivery of chemical penetration enhancers into skin during transdermal sonophoresis — Insight into the observed synergism
The synergism between low-frequency sonophoresis (LFS) and chemical penetration enhancers (CPEs), especially surfactants, in transdermal enhancement has been investigated extensively since this phenomenon was first observed over a decade ago. In spite of the identifying that the origin of this syner...
Main Authors: | Polat, Baris E., Deen, William M., Langer, Robert, Blankschtein, Daniel |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/99235 https://orcid.org/0000-0001-5966-6462 https://orcid.org/0000-0002-7836-415X https://orcid.org/0000-0003-4255-0492 |
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