Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science

In recent years, there has been a surge in methods to synthesize geometrically and chemically complex microparticles. Analogous to atoms, the concept of a “periodic table” of particles has emerged and continues to be expanded upon. Complementing the natural intellectual curiosity that drives the cre...

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Main Authors: Helgeson, Matthew E., Chapin, Stephen C., Doyle, Patrick S.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99348
https://orcid.org/0000-0001-9384-4023
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author Helgeson, Matthew E.
Chapin, Stephen C.
Doyle, Patrick S.
author2 Massachusetts Institute of Technology. Department of Chemical Engineering
author_facet Massachusetts Institute of Technology. Department of Chemical Engineering
Helgeson, Matthew E.
Chapin, Stephen C.
Doyle, Patrick S.
author_sort Helgeson, Matthew E.
collection MIT
description In recent years, there has been a surge in methods to synthesize geometrically and chemically complex microparticles. Analogous to atoms, the concept of a “periodic table” of particles has emerged and continues to be expanded upon. Complementing the natural intellectual curiosity that drives the creation of increasingly intricate particles is the pull from applications that take advantage of such high-value materials. Complex particles are now being used in fields ranging from diagnostics and catalysis, to self-assembly and rheology, where material composition and microstructure are closely linked with particle function. This is especially true of polymer hydrogels, which offer an attractive and broad class of base materials for synthesis. Lithography affords the ability to engineer particle properties a priori and leads to the production of homogenous ensembles of particles. This review summarizes recent advances in synthesizing hydrogel microparticles using lithographic processes and highlights a number of emerging applications. We discuss advantages and limitations of current strategies, and conclude with an outlook on future trends in the field.
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spelling mit-1721.1/993482022-09-29T22:44:58Z Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science Helgeson, Matthew E. Chapin, Stephen C. Doyle, Patrick S. Massachusetts Institute of Technology. Department of Chemical Engineering Helgeson, Matthew E. Chapin, Stephen C. Doyle, Patrick S. In recent years, there has been a surge in methods to synthesize geometrically and chemically complex microparticles. Analogous to atoms, the concept of a “periodic table” of particles has emerged and continues to be expanded upon. Complementing the natural intellectual curiosity that drives the creation of increasingly intricate particles is the pull from applications that take advantage of such high-value materials. Complex particles are now being used in fields ranging from diagnostics and catalysis, to self-assembly and rheology, where material composition and microstructure are closely linked with particle function. This is especially true of polymer hydrogels, which offer an attractive and broad class of base materials for synthesis. Lithography affords the ability to engineer particle properties a priori and leads to the production of homogenous ensembles of particles. This review summarizes recent advances in synthesizing hydrogel microparticles using lithographic processes and highlights a number of emerging applications. We discuss advantages and limitations of current strategies, and conclude with an outlook on future trends in the field. National Science Foundation (U.S.) (Grant DMR-1006147) Novartis-MIT Center for Continuous Manufacturing National Institute for Biomedical Imaging and Bioengineering (U.S.) (Grant R21EB008814) 2015-10-15T17:54:25Z 2015-10-15T17:54:25Z 2011-01 2010-12 Article http://purl.org/eprint/type/JournalArticle 13590294 http://hdl.handle.net/1721.1/99348 Helgeson, Matthew E., Stephen C. Chapin, and Patrick S. Doyle. “Hydrogel Microparticles from Lithographic Processes: Novel Materials for Fundamental and Applied Colloid Science.” Current Opinion in Colloid & Interface Science 16, no. 2 (April 2011): 106–117. https://orcid.org/0000-0001-9384-4023 en_US http://dx.doi.org/10.1016/j.cocis.2011.01.005 Current Opinion in Colloid & Interface Science Creative Commons Attribution-Noncommercial-NoDerivatives http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier PMC
spellingShingle Helgeson, Matthew E.
Chapin, Stephen C.
Doyle, Patrick S.
Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science
title Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science
title_full Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science
title_fullStr Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science
title_full_unstemmed Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science
title_short Hydrogel microparticles from lithographic processes: Novel materials for fundamental and applied colloid science
title_sort hydrogel microparticles from lithographic processes novel materials for fundamental and applied colloid science
url http://hdl.handle.net/1721.1/99348
https://orcid.org/0000-0001-9384-4023
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