Highly stable, ligand-clustered “patchy” micelle nanocarriers for systemic tumor targeting
A novel linear-dendritic block copolymer has been synthesized and evaluated for targeted delivery. The use of the dendron as the micellar exterior block in this architecture allows the presentation of a relatively small quantity of ligands in clusters for enhanced targeting, thus maintaining a long...
Main Authors: | Poon, Zhiyong, Lee, Jung Ah, Huang, Shenwen, Prevost, Richard J., Hammond, Paula T. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/99388 |
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