A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

Phagocytosis can be induced via the engagement of Fcγ receptors by antibody-opsonized material. Furthermore, the efficiency of antibody-induced effector functions has been shown to be dramatically modulated by changes in antibody glycosylation. Because infection can modulate antibody glycans, which...

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Bibliographic Details
Main Authors:	Ackerman, Margaret E., Moldt, Brian, Wyatt, Richard T., Dugast, Anne-Sophie, McAndrew, Elizabeth G., Tsoukas, Stephen, Jost, Stephanie, Berger, Christoph T., Sciaranghella, Gaia, Liu, Qingquan, Irvine, Darrell J., Burton, Dennis R., Alter, Galit
Other Authors:	Massachusetts Institute of Technology. Department of Biological Engineering
Format:	Article
Language:	en_US
Published:	Elsevier 2015
Online Access:	http://hdl.handle.net/1721.1/99423

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