Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness
Pericytes surround capillary endothelial cells and exert contractile forces modulating microvascular tone and endothelial growth. We previously described pericyte contractile phenotype to be Rho GTPase- and α-smooth muscle actin (αSMA)-dependent. However, mechanisms mediating adhesion-dependent shap...
Main Authors: | Kotecki, Maciej, Zeiger, Adam S., Van Vliet, Krystyn J., Herman, Ira M. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/99426 https://orcid.org/0000-0001-5735-0560 |
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